Frost & Sullivan Recognizes DNAnexus as the Enabling Technology Leader in the Global Genomics Industry

F&SAt DNAnexus, we’re honored to be recognized by Frost & Sullivan as one of the most significant enabling technologies driving industry-changing innovation within the genomics community globally. Frost & Sullivan research involves extensive primary and secondary research across the entire value chain of specific products. Against the backdrop of this research, Frost & Sullivan evaluated DNAnexus on two key factors — Technology Leverage and Customer Impact — and compared DNAnexus to other industry players.  DNAnexus’ overall rating was significantly higher than the other industry players, resulting in the Best Practice recognition.

Quadrant

Solve for Scale

As next-generation sequencing (NGS) projects take off with the goal of sequencing tens or hundreds of thousands of genomes, there is a crucial need for a solution that can handle this tremendous amount of data being produced.

As DNAnexus’ own VP of Science, Andrew Carroll puts it, “Life science companies are missing a management system for dealing with petabytes of data and billions of objects. There are challenges of operating at scale – it’s not that difficult to do something that will work once or a hundred times, but when it comes to have the same system work hundreds of thousands or millions of times, there are a lot of random errors and other lower-level problems that turn out to be a big deal.” You can read more on why life sciences and genomics markets are finding cloud approaches more appealing here.

These companies are in need of an efficient way to upload, store, share, and analyze the increasingly massive amounts of data being generated. At DNAnexus, we’re harnessing the power of the cloud to do just that. We are committed to innovation in this area, powering industry and academia as they continually aim to take on more genomic data.

Secure Solutions

Because it’s uniquely tied to an individual, genomic data can be regarded as some of the most sensitive data collected. As organizations seek to make advancements in this field, they need to ensure the sensitivity of genomic information is preserved.

DNAnexus offers layers of platform features and accreditation to support an exceptionally strong security and compliance profile. DNAnexus is continually audited and certified by an independent 3rd party for compliance with ISO 27001, an internationally recognized Information Security Management System and accompanying controls, enabling DNAnexus to address a broad range of global compliance regimes. . These include HIPAA, CAP/CLIA, GCP/GLP, dbGaP, FedRAMP, and European Data privacy laws.  

Collaborative Community

Frost & Sullivan acknowledges the collaborative nature of our platform as one of its key strengths. A dataset is only as good as is the ability to access it. Additionally, as sequencing projects scale, so can the number of organizations working together to draw conclusions.

DNAnexus provides a network of collaborators in the genomics community the ability to share, transfer, access, integrate, and analyze this data – all securely and compliantly within the cloud.  DNAnexus is the Platform of choice for leading academic core labs and consortia, including the Stanford Center for Genomics and Personalized Medicine, ENCODE, 3000 Rice Genomes Project, precisionFDA and more.

Poised for Success

Frost & Sullivan recognizes our commitment to solve some of the biggest challenges facing the field of genomics. DNAnexus, and its broad network of partners, provides pharmaceutical and biotech companies, global diagnostic test providers, genome centers, and sequencing service providers secure and compliant infrastructure and scientific support to solve today’s genomic challenges faster and more effectively than ever before. The company is the platform supporting some of the largest genomic sequencing projects in the world, such as Regeneron Genetics Center, and the underlying platform for precisionFDA, the FDA’s forward-thinking initiative to evaluate the accuracy and reproducibility of next-generation sequencing bioinformatics pipelines.

We’ve been at the forefront of employing the cloud as the ideal platform for genomics and scientific computing and we’re excited to continue our work to create the global network for genomics. You can read the full Frost & Sullivan report here.

Curious to see how our Platform works? Request a demo

Webinar Series: Enabling PacBio Long-Read Bioinformatics in the Cloud

We are excited to be hosting, in collaboration with our partner PacBio, an inaugural webinar series focused on best practices for analyzing SMRT® Sequencing data.

De novo genome assembly and structural variant calling are complex tasks, which can require massive computational resources to weave long-reads into a final, polished assembly or run a variety of SV detection methods across multiple data types. Reference genome assembly is done far less frequently than whole genome sequencing, just as the case with SV detection vs. SNP detection.  DNAnexus and PacBio are collaborating to make tools and resources easily accessible and enabling researchers to take long-read bioinformatics to new heights. Learn about today’s best practices for PacBio sequencing data.

Session 1: Rapid Reference-Quality Genome Assembly
May 4, 2016
8:00am PST, 11:00am EST, 5:00pm CET

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Brett Hannigan, PhD, Director, Scientific Partnerships at DNAnexus, will present how running FALCON on the DNAnexus Platform can provide a fast, accurate, and cost-efficient solution for de novo genome assembly. In this webinar, we’ll examine the challenges around assembling the tobacco genome (comprised of 4.5 billion base pairs), which is tetraploid in nature and highly repetitive.

Session 2: Simplifying Structural Variant Discovery
June 16, 2016
8:00am PST, 11:00am EST, 5:00pm CET

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AndrewAndrew Carroll, PhD, Vice President, Science at DNAnexus will present how current solutions that use PacBio data can greatly improve the accuracy of SV-calling by using fast and easy to run cloud-optimized apps (PBHoney, Parliament, & Sniffles). We will also explore the current work we are doing with Genome in a Bottle (GIAB) to develop high confidence truth sets for structural variants. Finally, Andrew will discuss how sequencing coverage correlates with the ability to accurately call structural variants, to inform decisions about the ideal depth to sequence.

Who should attend?
Researchers currently working with or those who desire to work with PacBio RSII and/or Sequel data.

At Bio-IT World: Technological Innovation Advancing Genomic Science and Medicine

2Bio-IT World Conference & Expo comes early this year (April 4-7th), where more than 3,000 researchers, life science, pharmaceutical, clinical, and IT professionals descend upon Boston.  If you’re headed to Bio-IT World, please stop by the DNAnexus booth (#317) to explore and discuss our latest projects, new datasets, and tools.

This year, Big Data is a featured theme at the event. Our friend and collaborator, Dr. Taha Kass-Hout (Chief Health Informatics Officer and Director of the FDA’s Office of Health Informatics) kicks off the Big Data: Sharing vs. Privacy vs. Security in Healthcare session (Track 3, Thursday at 2:00pm) with an overview of precisionFDA, the new community platform for NGS assay evaluation and regulatory science exploration. Additional fascinating talks follow: John E. Mattison (Co-Chair, eHealth Workgroup, Global Alliance for Genomics and Health) will present emerging initiatives from the GA4GH and Robert Grossman (Director, Center for Data Intensive Science) will discuss large-scale data commons for genomic and clinical data.  The final session includes those experts along with John M. Conley (Robinson Bradshaw & Hinson), Andrew K. Porter (Merck & Co.), and Mollie Shields-Uehling (SAFE-BioPharma Assoc.) for a panel discussion looking at data sharing innovations and the regulatory environment.

Best_Practices_Logo_2016_finalist-blue (1)Precision medicine continues to be a strong theme for 2016, bolstered by President Obama’s recent Precision Medicine Initiative (PMI) Summit. At DNAnexus, we like to think of genetic data as the original Big Data, and we are passionate about Big Data’s role in advancing medical discovery and treatments. We are proud to announce that precisionFDA is a Bio-IT World Best Practice Award finalist.  The Best Practice Award highlights outstanding examples of how technological innovation can be powerful forces of change in the life sciences.  The precisionFDA platform was developed under contract for the FDA by DNAnexus, and currently provides over 1,000 users from nearly 500 organizations in the genomics community a sandbox for NGS assay evaluation and regulatory science exploration.  Be sure to be there when the winners are announced live on Wednesday, April 6th at 9:30am.

Dr. Taha Kass-Hout, Chief Health Informatics Officer and Director of FDA’s Office of Health Informatics, will be making a cameo appearance at the DNAnexus booth to answer questions and showcase the precisionFDA platform.  Learn how precisionFDA is leveraging community participation to advance regulatory science in the area of next-generation sequencing – DNAnexus is proud to have collaborated with the FDA to develop the community platform.  

PrecisionFDA Demo & Dr Taha Meet & Greet at the DNAnexus Booth (#317)

  • Wednesday, April 6th at 10:00am-11:00am
  • Wednesday, April 6th at 5:30pm-6:30pm

DNAnexus Booth (#317) Activities
Unite your workflows. DNAnexus offers end-to-end tailored solutions. We’ll be demoing a few upstream and downstream partner options at our booth:  Sapio
Sciences LIMS, Pacific Biosciences tools, and WuXi NextCODE Cloud platform.    

Wednesday, April 6th
3:25pm Sapio’s Exemplar NGS LIMS Demo
See how the integration of the DNAnexus platform with Sapio Sciences’ LIMS solution is enabling seamless integration with bioinformatics operations, enabling secure scalability and flexible workflows.

Thursday, April 7th
10:00am WuXi NextCODE Cloud Demo
Learn how the WuXi NextCODE Cloud — powered by DNAnexus — is accelerating the use of genomics to benefit patients worldwide. China cloud solution now available.

1:20pm PacBio de novo Assembly & SV Analysis Tools Demo
Demo the latest PacBio tools on the DNAnexus platform. See how complex bioinformatics is made simple.

Must-See Presentations
We’re proud to support our customers who push the envelope in advancing genomic science and medicine.  Be sure not to miss these talks!

Track 3 Software Applications & Services:  Regeneron Genetics Center’s  Use of the DNAnexus Annex in the Amazon Cloud for Large-Scale NGS Downstream Compute
Presenter:  Christopher Sprangel, Director, IT, Human Genetics, Genome Informatics, Regeneron Genetics Center and Nathan Wallace, Founder & CEO, Turbot
When:  Wednesday, April 6 at 2:25pm

Track 3 Software Applications & Services:  Featured Presentation: precisionFDA
Presenter:  Taha A. Kass-Hout, MD, MS, Chief Health Informatics Officer & Director, Office of Health Informatics, FDA
When:  Thursday, April 7 at 2:00pm

Track 3 Software Applications & Services: Panel Discussion:  How will data sharing innovations fare in the regulatory environment?
Moderator:  John M. Conley, JD, PhD, Robinson Bradshaw & Hinson
Panelists:  Robert Grossman, PhD, University of Chicago, Taha A. Kass-Hout, MD, MS, FDA, John E Mattison, MD, Kaiser Permanente, Andrew K. Porter, Merck & Co., and Mollie Shield-Uehling, SAFE-BioPharma Association
When:  Thursday, April 7 at 3:30pm

To learn more about DNAnexus and see a demo of the DNAnexus Platform, visit booth #317 in the exhibit hall at the Bio-IT World Conference & Expo.