Run the Mercury Variant-Calling Pipeline on Your Own Data

HGSC Baylor College of MedicineMercury, designed by the Human Genome Sequencing Center at Baylor College of Medicine (HGSC), is used as the core variant-calling pipeline for the CHARGE consortium. The Mercury pipeline is a semi-automated and modular set of tools for the analysis of NGS data in clinically focused studies. HGSC designed the pipeline to identify mutations from genomic data, setting the stage for determining the significance of these mutations as a cause of serious disease.

Thanks to HGSC’s work with us, the Mercury pipeline is now freely available to any DNAnexus user. The Mercury pipeline is located in the applets folder of the  HGSC_Mercury project. You can find the project, along with everything you need to run the applet, under the ‘Featured Projects’ section on your home page.  Login to DNAnexus or create an account today to get started immediately.

Inside the Mercury Project

  • Both whole genome and exome samples
  • All annotation and reference data required
  • Pre–configured workflow (just drag & drop your inputs)

Results from the Mercury pipeline will be made up of a set of annotated variants from your data sample. You’ll also see all of the biologically significant data that applies to the variants from the Baylor College of Medicine database, using their Cassandra annotation tool. You can easily visualize the mappings and variant calls within our integrated genome browser.

Congratulations to Our Newest iPad Winners!

We’re delighted to see that more and more people are signing up to keep updated on the status of the upcoming launch of our new platform. As promised, each month we have drawn a name from that growing list to be the lucky winner of a new iPad.

We have two new winners to announce:

For July, the lucky person was Marie Fahey, a bioinformatics analyst with Asuragen. And for June, the winner was Ravi Madduri, a fellow in the Computation Institute at the University of Chicago. Congratulations to both!

If you haven’t already done so, don’t forget to sign up on dnanexusx.com to be the first to know when we unveil the new platform.

First Two iPad Winners Announced, and Another Chance to Win!

Many thanks to everyone who has signed up so far at our DNAnexusX landing
page to find out about the new platform we’ll be launching later this year.
Our developers are working furiously on the final touches, and we can’t
wait to give you all a peek at the new product.

In addition to the updates we’ll be sending about the new platform as we get
closer to launch, people who sign up on the landing page are also entered
into a monthly drawing for a free iPad.  We’re delighted to announce that
our winner for April was Mike Warfe, solutions architect at Case Western
Reserve University, and our winner for May is Bingbing Yuan in
bioinformatics at the Whitehead Institute.
Congratulations to both of them!

We’ve more iPad giveaways planned for June and July, so it’s not too
late to sign up at the landing page to be automatically entered to win.
Simply go to dnanexusx.com and enter your e-mail address.