Upgrading to TLS 1.2

As a part of our continued efforts to maintain the highest security standards on the DNAnexus Platform, we will deprecate support of TLS 1.0 and TLS 1.1 on October 15th, 2017. We have been communicating this proposed change, and most of the customers and users have upgraded.

If you are a user that still has programs or processes using TLS 1.0 or 1.1 when interfacing with the DNAnexus Platform you will need to take a few simple steps to upgrade. Please follow the instructions below to upgrade to TLS 1.2.

What is TLS?
TLS stands for “Transport Layer Security” and is a protocol that ensures connections made to a remote endpoint are the intended destination through encryption and endpoint identity verification. DNAnexus web and API connections use TLS as a key security component, thus it is important that the latest version of TLS is supported.

What do I need to do?
For macOS/OS X Users:
If you are using the DNAnexus Platform SDK (a.k.a. dx-toolkit) with the Python version provided with your operating system, you will need to install an alternative Python version with TLS 1.2 support. We suggest using the Homebrew package manager to install Python version 2.7.13:
Install Homebrew using the instructions at https://brew.sh/.

Once Homebrew is installed, run the following command in your terminal prompt:
brew install python

Once the Python version is installed follow the instructions at https://wiki.dnanexus.com/Downloads to download, unpack, and activate the latest dx-toolkit release.

For Internet Explorer Web Browser Users:
If you use Internet Explorer version 10 or earlier, you will need to upgrade your web browser to Internet Explorer 11 or later.

For All Other Users:
If you use a PC, or if your web browser is Internet Explorer 11 or later, Chrome, Firefox, or Safari, we do not expect that your access to DNAnexus will be impacted by this upgrade.

If you are impacted, please make the necessary modifications by October 15th, 2017 in order to maintain continued access to DNAnexus. Please do not hesitate to contact support@dnanexus.com with any questions or concerns.

DNAnexus and Saphetor Collaborate for Seamless Integration of Tertiary Analysis Solution

DNAnexus has teamed up with Saphetor, a leading variant analysis company, to build a sample-in, report-out genomic analysis solution. Saphetor annotates and classifies genetic variants from next-generation sequencing (NGS) data to help clinicians quickly and accurately diagnose disease to make faster, more precise treatment decisions. Saphetor’s technology is now available on the DNAnexus cloud-based platform.

Saphetor has built a powerful genome interpretation engine by integrating more than 30 public and licensed databases containing genotype, phenotype, variant, drug, and clinical trial information. Automated annotation ensures a comprehensive understanding of variant significance and implication for disease. Each variant is annotated with gene and functional position, protein functional impact, population allele frequencies, and pathogenicity prediction scores. Using the DNAnexus-Saphetor integration, researchers globally can conduct secure, whole-genome analysis leveraging Saphetor’s databases containing 33 billion variant annotation points.

Data from the DNAnexus Platform is exported to Saphetor via a secure API, enabling customers to take advantage of this comprehensive analysis solution. Saphetor’s powerful user interface allows customers to interactively browse and use powerful filters on the annotated and classified variant list in an intuitive fashion. Click on the image below to see a sample of the variant analysis interface.

Together with the scalability and high-performance computing power of the DNAnexus Platform, and Saphetor’s variant browsing tools, customers can quickly move from NGS data analysis to interpretation. Researchers can discover which variants have a functional impact on disease in the hopes of accelerating the implementation of precision medicine. We are excited about our collaboration with Saphetor to offer a secure and scalable environment to power an end-to-end analytical solution for genomic biomarker discovery and interpretation.

Interested in trying out Saphetor’s technology on DNAnexus? Get in touch with a member of our Science Team.

The New UI: Sleeker. Modern. Intuitive.

We are pleased to announce a design refresh of the DNAnexus web user interface! The new, modern interface incorporates visual enhancements that make the most common tasks and interactions intuitive and delightful, without changing the underlying functions that power your biomedical research. Explore some of the updates below, highlighted in yellow.

Project List

Your list of projects and files has a sleeker layout and more intuitive filtering system. Looking for your Bookmarks? The Bookmarks tab has been renamed to Saved Filters so you can quickly find and access the projects you’re looking for.

Project Page

Managing workflows has never been easier. The main actions are listed using clear, modernized icons to help you know exactly which steps to take next. Each file also has a context menu. Clicking on these three dots will help you accomplish actions such as view, copy, delete, and download one item at a time. You can still apply bulk action to all the files by clicking the icons at the top of the page.

App Library

The available apps are displayed in a simplified and visually appealing manner. The inputs and outputs of each tool are clearly shown, and finding the appropriate app for your analysis is now easier than ever. 

Billing Information

Your user settings have been reorganized to show your billing information in one distinct location. This will help you easily review your budget, spend, and remaining funds.

We hope these changes make using the DNAnexus web interface an intuitive and seamless experience. If you have any questions about the updates, let us know at support@dnanexus.com.