Join DNAnexus for a Lunchtime Workshop at ASHG

Whether you join us for lunch to explore the dark matter of ENCODE or visit our booth (#507) to check out the latest updates and get a demo of DNAnexus, we’d love to catch up with you at ASHG. Plus, be entered to win an iPod Shuffle, when introducing yourself at the DNAnexus booth.

 

kundaje encodeWe are honored to have Dr. Anshul Kundaje, research scientist at MIT, review his latest ENCODE consortium paper and share insights into gene regulation. By looking at 119 transcription factors and regulatory proteins, Kundaje’s team found that chromatin diversity at the regulatory level is the norm, rather than the exception.

 

During this lunchtime talk you’ll discover how Kundaje and team used DNAnexus to process and map some 5 billion reads and identified chromatin patterns via a newly developed probabilistic mapping tool, the Clustered AGgregation Tool (CAGT). The clustering approach yielded dramatically different results compared to the standard method of averaging chromatin marks across populations. Importantly, Kundaje’s team was able to identify about 25 “metapatterns,” or signatures that represent the diversity of modifications across binding sites and cell types. These distinct patterns will be valuable for other scientists examining chromatin modifications and making inferences about what those changes are doing in the genome.

 

Details

• Wednesday, November 7th, 12:45 – 2:15 pm
• Moscone Center, Room 301 (Esplanade Level)
• Boxed lunch & refreshments will be provided!

 

Agenda

Introduction
Brigitte Ganter, Ph.D., Director of Product Marketing, DNAnexus

Ubiquitous Heterogeneity and Asymmetry of the Chromatin Environment at Human Regulatory Elements
Anshul Kundaje, Ph.D., Research Scientist MIT

DNAnexus: A Collaborative and Scalable Data Technology Platform
Andreas Sundquist, Ph.D., CEO and Co-founder, DNAnexus

 

Explore the data yourself; you’ll find the 20 samples accessible via DNAnexus in our Public Data folder, labeled Encode.

 

Congratulations to Our Newest iPad Winners!

We’re delighted to see that more and more people are signing up to keep updated on the status of the upcoming launch of our new platform. As promised, each month we have drawn a name from that growing list to be the lucky winner of a new iPad.

We have two new winners to announce:

For July, the lucky person was Marie Fahey, a bioinformatics analyst with Asuragen. And for June, the winner was Ravi Madduri, a fellow in the Computation Institute at the University of Chicago. Congratulations to both!

If you haven’t already done so, don’t forget to sign up on dnanexusx.com to be the first to know when we unveil the new platform.

First Two iPad Winners Announced, and Another Chance to Win!

Many thanks to everyone who has signed up so far at our DNAnexusX landing
page to find out about the new platform we’ll be launching later this year.
Our developers are working furiously on the final touches, and we can’t
wait to give you all a peek at the new product.

In addition to the updates we’ll be sending about the new platform as we get
closer to launch, people who sign up on the landing page are also entered
into a monthly drawing for a free iPad.  We’re delighted to announce that
our winner for April was Mike Warfe, solutions architect at Case Western
Reserve University, and our winner for May is Bingbing Yuan in
bioinformatics at the Whitehead Institute.
Congratulations to both of them!

We’ve more iPad giveaways planned for June and July, so it’s not too
late to sign up at the landing page to be automatically entered to win.
Simply go to dnanexusx.com and enter your e-mail address.