Join Us at Bio-IT World for a Personalized Demo and Chance to Win an iPad Mini!

Next week kicks off the annual Bio-IT World Conference & Expo, one of the best conferences dedicated to bioinformaticians and computational biologists. We look forward to it every year for the opportunity to rub elbows with die-hard developers, IT powerhouses, and the truly remarkable scientists who are just as comfortable working with lines of code as others are with lines of cells. Last year the meeting had more than 2,500 attendees from all over the world; it’s a can’t-miss venue for people who work hard to make sure the computational side of biology functions properly.

In that spirit, we hope to meet many of you at our booth (#311) for a personalized demo of the new DNAnexus, our cloud-based genomics platform. For the bioinformatics professional, the new DNAnexus eliminates up-front commitment to expensive hardware and maintenance. And since DNAnexus leverages Amazon Web Services for scalable and cost-effective data storage and computing, a research lab can access these resources, as there is need. The new DNAnexus is now in beta and you can request access for a free account today.IPad Mini Giveaway

To sweeten your personalized test drive of the new DNAnexus platform at Bio-IT World, we are giving away an iPad Mini! Here’s how to enter:

1. Sign up for a beta account
2. Upload your data so you can test-drive our system
3. Visit DNAnexus in booth #311 for a chance to win

DNAnexus scientists will be on hand to offer a custom data analysis and answer any questions you may have. This is a perfect opportunity to see how our new platform will perform in your lab! Even if you don’t have time to upload your data ahead of time, please stop by to learn more about the new platform and shoot the bioinformatics breeze.

Plus, join us in our booth for daily 10-minute mini-sessions during meeting breaks. We’ll be spotlighting a few new DNAnexus features, including compliance, collaboration and app building.

Wednesday – April 10th

10:00 am Instant Collaboration:
Compliance Meets Collaboration: Together at Last
Vince Ramey, Ph.D., Scientist, DNAnexus
3:30 pm App Building:
Build an App & Share With Your Team in 10 Minutes
Andrey Kislyuk, Ph.D., Sr. Engineer, DNAnexus

Thursday – April 11th

10:30 am App Building:
Build an App & Share With Your Team in 10 Minutes
Andrey Kislyuk, Ph.D., Sr. Engineer, DNAnexus
1:30 pm Instant Collaboration:
Compliance Meets Collaboration: Together at Last
Vince Ramey, Ph.D., Scientist, DNAnexus

Dispelling the Myths of the Cloud

cloud computing in genomicsWhat comes to mind when you hear the word “cloud”? Does the Amazon cloud immediately pop into your head?

Despite the cloud’s widespread recognition in the media, many are still uncertain about the benefits of cloud computing.  In a recent national survey, 95% of respondents who claimed they have never used the cloud actually have. In fact, they do so unwittingly nearly everyday via online banking and shopping, social networking, emailing etc.

Some scientists still seem skeptical of the cloud’s place in next-generation sequencing. If you tend to gravitate to skepticism, please read my article, Dispelling the Myths of the Cloud for the Skeptical Scientist, on BitesizeBio.com.

It provides an overview of how the cloud can be useful to scientists in a multitude of ways, such as infinite scalability, enabling instant and limitless access to storage and compute resources, eliminating up-front commitment to expensive hardware. Another advantage, Data security, is the cloud’s core competency, which cannot be measured up to any other internal infrastructure.

The “cloud” may be generating a lot of buzz in the NGS community, but is it worthy of all the hype? It appears that all signs point to yes.

Join DNAnexus for a Lunchtime Workshop at ASHG

Whether you join us for lunch to explore the dark matter of ENCODE or visit our booth (#507) to check out the latest updates and get a demo of DNAnexus, we’d love to catch up with you at ASHG. Plus, be entered to win an iPod Shuffle, when introducing yourself at the DNAnexus booth.

 

kundaje encodeWe are honored to have Dr. Anshul Kundaje, research scientist at MIT, review his latest ENCODE consortium paper and share insights into gene regulation. By looking at 119 transcription factors and regulatory proteins, Kundaje’s team found that chromatin diversity at the regulatory level is the norm, rather than the exception.

 

During this lunchtime talk you’ll discover how Kundaje and team used DNAnexus to process and map some 5 billion reads and identified chromatin patterns via a newly developed probabilistic mapping tool, the Clustered AGgregation Tool (CAGT). The clustering approach yielded dramatically different results compared to the standard method of averaging chromatin marks across populations. Importantly, Kundaje’s team was able to identify about 25 “metapatterns,” or signatures that represent the diversity of modifications across binding sites and cell types. These distinct patterns will be valuable for other scientists examining chromatin modifications and making inferences about what those changes are doing in the genome.

 

Details

• Wednesday, November 7th, 12:45 – 2:15 pm
• Moscone Center, Room 301 (Esplanade Level)
• Boxed lunch & refreshments will be provided!

 

Agenda

Introduction
Brigitte Ganter, Ph.D., Director of Product Marketing, DNAnexus

Ubiquitous Heterogeneity and Asymmetry of the Chromatin Environment at Human Regulatory Elements
Anshul Kundaje, Ph.D., Research Scientist MIT

DNAnexus: A Collaborative and Scalable Data Technology Platform
Andreas Sundquist, Ph.D., CEO and Co-founder, DNAnexus

 

Explore the data yourself; you’ll find the 20 samples accessible via DNAnexus in our Public Data folder, labeled Encode.